How is light chain nephropathy classified?
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How is light chain nephropathy classified?
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@tamir Various glomerular abnormalities that are caused by the deposition of these monoclonal immunoglobulins (or their heavy-chain or light-chain subunits) and are broadly classified into 2 categories, organized or nonorganized, depending on the pattern of deposition.
Organized deposits include the following:
Fibrillar (amyloidosis)
Microtubular (cryoglobulinemia, immunotactoid glomerulonephritis)
Nonorganized, granular deposits include the following:Monoclonal immunoglobulin deposition disease (MIDD)
Light-chain, heavy-chain, and light- and heavy-chain deposition disease