Glucagon Analog Stops Hypoglycemia Faster Than Carbs
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Dasiglucagon, a glucagon analog approved for treating severe hypoglycemia, also appeared to be effective and highly acceptable for patients with type 1 diabetes with nonsevere hypoglycemia in a controlled, crossover study of 24 patients. In the head-to-head comparison with the main nonpharmacologic option for treating nonsevere hypoglycemia — ingestion of fast-acting carbohydrates — dasiglucagon (Zegalogue) produced similar times within the target range for blood glucose levels but worked faster, shaving 5 minutes off the median time it took for patients to achieve euglycemia following self-administration of the agent compared with the median lag using orally ingested carbohydrates, Christian Laugesen, MD, said at the American Diabetes Association (ADA) 82nd Scientific Sessions.
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@somraj Faster action and a higher rate of resolution may, in part, explain the high level of satisfaction with dasiglucagon by patients in the study. When the researchers asked participants at the end of the open-label study how likely they were to use dasiglucagon as part of their diabetes management, 88% said they would be very likely to continue using the agent, with an additional 8% saying that they would likely use it,