Age at Chemotherapy Linked to Fertility Problems Later
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With most patients surviving childhood cancer, the impact of chemotherapy on fertility in adulthood is a critical concern. According to a recent report, because there is uncertainty as to which patients are at risk for fertility problems, it is difficult to decide which patients should be offered fertility preservation treatment. Findings from this study help address the issue by identifying girls at higher risk for fertility problems later in life.
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@humbly The team reviewed 57 young female patients with cancer whose ovarian hormone levels following completion of chemotherapy had been documented and who had entered survivorship programs at Penn State Health from 2008–2017. Patients' ages ranged from 2–21 years at time of diagnosis, and they were split equally between those diagnosed before age 13 and those diagnosed after that age. Diagnoses included leukemia, Hodgkin's lymphoma, and solid tumors.