No Need for Intensive Follow-up of Endometrial Cancer
Women with endometrial cancer do not need to undergo intensive follow-up, say experts.
Results from the TOTEM trial show that intensive follow-up does not improve overall survival (OS) compared to a much less intensive surveillance approach, even for high-risk patients.
"[T]here is no need to routinely add vaginal cytology, laboratory, or imaging investigations to the MIN [minimalist] regimens used in this trial," conclude Paolo Zola, MD, and colleagues on behalf of the TOTEM collaborative group.
The study was published September 1, 2022 in the Journal of Clinical Oncology.
In an accompanying editorial, Amanda Fader, MD, Johns Hopkins School of Medicine, Baltimore, Maryland, and colleagues endorse the authors' recommendations.
@vishal Despite these guidelines, significant practice variability exists among oncologists, with many preferring intensive surveillance, likely stemming from the belief among patients and physicians that if a recurrence is detected early, there is a higher likelihood of disease control or improved survival