High Bone Density Found in Women With Hypoparathyroidism
Among women with hypoparathyroidism, bone mineral density (BMD) was increased, and there was no increase in fracture risk nor in fracture prevalence compared with matched control women with normal levels of parathyroid hormone in a cross-sectional, case-control study that involved 71 women.
@sampriti Few previous studies assessed fracture risk in people with hypoparathyroidism, and reported studies have had contradictory findings. Chronic deficiency of parathyroid hormone (PTH) results in increased bone mass and improved bone strength, which could reduce fracture risk. But low PTH levels causes low bone turnover, which may cause bones to be fragile, thereby increasing the risk of microdamage.
The study collected data on bone geometry and microarchitecture with high-resolution peripheral quantitative CT (HR-pQCT). Few prior studies have used this method for bone assessment of people with hypoparathyroidism.