How wasp bite leads to death?
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Hello, my 67 year old grandfather was stung by a swarm of wasps in a rural, semi forested area. He accidently disturbed a wasp hive while collecting firewood leading to the attack predominantly on the scalp, neck, upper limbs and lower limbs. This caused severe breathlessness and she was brought to the casualty in severe pain. On examination 29 sting bites were identified which resulted in swelling of face, shoulder and upper arms. He had a history of diabetes and vitiligo After 4 hours of admission patient had suddenly collapsed in the Intensive care Unit (ICU), the blood pressure and pulse was not recordable. After giving repeated Cardio Pulmonary resuscitation (CPR) he could not be revived. We all in our family are shattered by this. We cant figure out how it happened and how wasp bite leads to death.
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@tithi Active venom substances can cause direct venom cardio toxicity resulting in platelet aggregation and vasoconstriction. These vasoactive mediators can precipitate in myocardial ischemia either by hypotension or by increasing myocardial oxygen demand through direct inotropic or chronotropic effects. Serotonin, epinephrine and thromboxane’s induce platelet aggregation hastening the thrombus formation. Epinephrine that is often administered in the hospital setting of anaphylaxis can also aggravate myocardial ischemia, especially in elderly patients with coronary heart disease. The mechanisms responsible for myocardial infarction might be coronary artery spasm and/or secondary in situ thrombosis.